Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size:  One (1) Capsule
Amount Per Serving
%DV
Calories
0
 
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
 
0%+
Lactobacillus rhamnosus GG
83 mg (20 billion CFUs)
**
Inulin (Chicory root extract)
200 mg
**

Top Medical Research Studies

9
Effective treatment for IBS-C
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.

Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Read More
8
Lactobacillus rhamnosus protects gut barrier
We explored how Lactobacillus rhamnosus GG (LGG) interacts with intestinal barrier functions in the context of irritable bowel syndrome (IBS). Using human intestinal models, we found that LGG helps maintain barrier integrity when challenged with harmful substances from IBS patients.

Our findings revealed that LGG can prevent damage to tight junction proteins and lower permeability of the gut lining. However, LGG's beneficial effects were not replicated with its cell wall extracts, DNA, or boiled forms, indicating the importance of its live metabolites. This suggests that LGG may be a promising way to support gut health in IBS.
Read More
We explored the impact of inulin on irritable bowel syndrome (IBS), particularly focusing on its effect for those suffering from constipation. IBS is a widespread issue that brings significant social and financial burdens.

Our investigation revealed that inulin appears to play a beneficial role in managing symptoms by influencing bowel movements and improving stool consistency. It does this by altering the gut microbiota, which is increasingly recognized as an important factor in gastrointestinal health.

However, while the positive outcomes of inulin for IBS patients with constipation seem promising, more large-scale, randomized clinical trials are necessary to strengthen this evidence. It’s essential to ensure the findings are backed by solid data so that patients can confidently consider inulin as a viable treatment option.
Read More

Most Useful Reviews

7.5
Improved bowel function
Great probiotics! I noticed an improvement in my bowel function after using antibiotics. I'm satisfied!
Read More
7.5
Effective digestion aid
This product is effective in addressing gas, bowel movements, and digestion, although it is rather pricey. It also helps with my gastritis, which is a relief when dealing with irritable bowel syndrome.
Read More
7.5
Comfortable bowel movements
I purchased the LG Lactobacillus for a significant 20 billion won, which made my bowel movements comfortable and alleviated any discomfort in my intestines.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7
  • All Researches
9
Effective treatment for IBS-C
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.

Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Read More
9
Lactobacillus rhamnosus improves IBS symptoms
We explored how Lactobacillus rhamnosus, part of a complex probiotic called Neobiotic Lactobalance®, impacts patients with irritable bowel syndrome (IBS) with diarrhea and antibiotic-associated diarrhea (AAD).

In a 21-day study involving 54 patients, significant improvements were noted. Diarrheal symptoms in IBS patients dropped markedly from 17 to 6 points, while AAD symptoms fell from 13 to just 3 points.

Overall, we saw that this probiotic not only normalized gut bacteria but also substantially eased symptoms, suggesting it can be a valuable part of managing these digestive disorders.
Read More
We investigated the effects of a new formulation containing Lactobacillus rhamnosus and Bifidobacterium longum, supplemented with vitamin B6, on patients with irritable bowel syndrome (IBS). In a well-structured, double-blind, controlled trial with 25 participants, we found significant improvements in symptoms like abdominal pain and bloating compared to placebo.

Specifically, abdominal pain decreased by nearly 49% and bloating by over 36%. Additionally, we observed enhancements in intestinal permeability and an increase in beneficial gut bacteria.

Overall, this promising treatment highlights the potential of using probiotics to manage IBS symptoms effectively.
Read More
We assessed the effectiveness of a non-alcoholic, fermented kombucha drink enriched with inulin and vitamins on individuals with constipation-predominant irritable bowel syndrome (IBS). This innovative study involved 40 participants who were randomly assigned to receive either the kombucha drink or plain water over a span of 10 days.

Our findings highlighted that those who consumed the kombucha drink experienced a notable increase in stool frequency—moving from an average of 0.60 to 0.85 bowel movements per day. Furthermore, the consistency of their stools improved significantly, indicating a shift from harder to softer stools, which benefits IBS sufferers.

Participants also reported feeling less discomfort related to incomplete bowel emptying after drinking the kombucha. In contrast, those in the control group did not experience such improvements, underscoring the potential benefits of inulin when combined with the unique properties of kombucha.

While the study revealed valuable insights into how a kombucha-based drink can enhance bowel health, it's essential to note that some symptoms did not show significant differences between groups—implying that while inulin may help, it is not a universal remedy for all IBS-related issues. Overall, our research suggests that kombucha enriched with inulin could be a promising supplement for those struggling with IBS symptoms, particularly constipation.
Read More
9
We explored the impact of a functional drink containing inulin, menthol, and pyridoxine on patients suffering from constipation-predominant irritable bowel syndrome (IBS-C). In our study, 49 participants, aged between 18 and 68 years and meeting the Rome III criteria, were divided into two groups. One group followed their standard diet plus two drinks a day for two weeks, while the control group maintained their usual diet without the drinks.

The results were promising. Those who consumed the functional drink experienced a notable improvement in bowel frequency and stool consistency, with an increase in daily bowel movements and a better Bristol stool scale score. Additionally, there was a significant reduction in abdominal pain, bloating, and the feeling of incomplete bowel emptying. Quality of life also received a boost, reflecting an enhanced well-being among participants.

However, we found that a significant number of participants reported experiencing heartburn after starting the treatment. This highlights the need for further adjustments in the drink’s formulation to mitigate these adverse effects. Overall, our findings suggest that a functional drink with inulin can improve various symptoms of IBS-C, while also making it clear that modifications may be necessary to address side effects like heartburn.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improved bowel function
Great probiotics! I noticed an improvement in my bowel function after using antibiotics. I'm satisfied!
Read More
7.5
Effective digestion aid
This product is effective in addressing gas, bowel movements, and digestion, although it is rather pricey. It also helps with my gastritis, which is a relief when dealing with irritable bowel syndrome.
Read More
7.5
Comfortable bowel movements
I purchased the LG Lactobacillus for a significant 20 billion won, which made my bowel movements comfortable and alleviated any discomfort in my intestines.
Read More

Frequently Asked Questions

7.5
Improved bowel function
Great probiotics! I noticed an improvement in my bowel function after using antibiotics. I'm satisfied!
7.5
Effective digestion aid
This product is effective in addressing gas, bowel movements, and digestion, although it is rather pricey. It also helps with my gastritis, which is a relief when dealing with irritable bowel syndrome.
7.5
Comfortable bowel movements
I purchased the LG Lactobacillus for a significant 20 billion won, which made my bowel movements comfortable and alleviated any discomfort in my intestines.
8
Probiotics may benefit IBS treatment
We explored how a special probiotic mix, including Lactobacillus rhamnosus, affects patients with Irritable Bowel Syndrome (IBS). Using an in vitro model, we found that this blend significantly improved the integrity of the intestinal barrier when exposed to substances from IBS patients.

Specifically, it helped to reduce the permeability issues caused by these substances, especially in patients with diarrhea and mixed bowel habits. Overall, this research suggests that probiotics like Lactobacillus rhamnosus can potentially support gut health in IBS.
7
Probiotics may alleviate IBS symptoms
We investigated the effectiveness and safety of a combination of microencapsulated sodium butyrate, probiotics, and short-chain fructooligosaccharides in people with irritable bowel syndrome (IBS).

In a randomized, double-blind, placebo-controlled trial with 120 adults, participants receiving the biotic mixture showed significant symptom relief by four weeks, with improved quality of life noted.

While some measures indicated benefits, like less urgency to defecate, other evaluations revealed no major differences between the treatment and placebo groups. Overall, this approach was found to be safe and well tolerated.
9
Lactobacillus rhamnosus improves IBS symptoms
We explored how Lactobacillus rhamnosus, part of a complex probiotic called Neobiotic Lactobalance®, impacts patients with irritable bowel syndrome (IBS) with diarrhea and antibiotic-associated diarrhea (AAD).

In a 21-day study involving 54 patients, significant improvements were noted. Diarrheal symptoms in IBS patients dropped markedly from 17 to 6 points, while AAD symptoms fell from 13 to just 3 points.

Overall, we saw that this probiotic not only normalized gut bacteria but also substantially eased symptoms, suggesting it can be a valuable part of managing these digestive disorders.
9
Effective treatment for IBS-C
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.

Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
5
Probiotic mixture offers limited IBS relief
We explored how a multi-species probiotic mixture, including Lactobacillus rhamnosus, affects patients with irritable bowel syndrome (IBS). In a study with 81 participants, we observed that after four weeks, those who took the probiotic had higher levels of beneficial bacteria and reported better relief from certain symptoms, particularly diarrhea. However, overall symptom improvement was similar between those receiving the probiotics and the placebo group. While our results show promise, they highlight that probiotics alone may not fully resolve IBS symptoms for everyone.
4
Probiotics show promise for children
We reviewed existing literature on probiotics for children’s gastrointestinal issues, including their potential benefits and safety. The expert consensus highlights that Lactobacillus rhamnosus GG is recommended for managing various conditions, such as intestinal infections and colic, earning a solid recommendation score.

However, we found that while Lactobacillus rhamnosus may help improve symptoms of irritable bowel syndrome, the evidence is limited. Therefore, its effectiveness in this area remains uncertain and requires further investigation.

References

  1. Barbaro MR, Bianco F, Cremon C, Marasco G, Stanghellini V, et al. A Probiotic Mixture of LR 32, BL 04, and BB 536 Counteracts the Increase in Permeability Induced by the Mucosal Mediators of Irritable Bowel Syndrome by Acting on Zonula Occludens 1. Int J Mol Sci. 2025;26. 10.3390/ijms26062656
  2. Gąsiorowska A, Romanowski M, Walecka-Kapica E, Kaczka A, Chojnacki C, et al. Efficacy and Safety of a Mixture of Microencapsulated Sodium Butyrate, Probiotics, and Short Chain Fructooligosaccharides in Patients with Irritable Bowel Syndrome-A Randomized, Double-Blind, Placebo-Controlled Study. J Clin Med. 2024;14. 10.3390/jcm14010006
  3. Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. 10.1038/s41598-024-72887-x
  4. Zhang L, Ni X, Jiang M, Du M, Zhang S, et al. Strains for Alleviation of Irritable Bowel Disease and Chronic Fatigue Syndrome. Microorganisms. 2024;12. 10.3390/microorganisms12061081
  5. Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. 10.33029/0042-8833-2023-92-4-92-103
  6. Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. 10.3390/nu12071999
  7. Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. 10.1111/eci.13201
  8. Ding FCL, Karkhaneh M, Zorzela L, Jou H, Vohra S. Probiotics for paediatric functional abdominal pain disorders: A rapid review. Paediatr Child Health. 2019;24:383. 10.1093/pch/pxz036
  9. Nocerino R, Di Costanzo M, Bedogni G, Cosenza L, Maddalena Y, et al. Dietary Treatment with Extensively Hydrolyzed Casein Formula Containing the Probiotic Lactobacillus rhamnosus GG Prevents the Occurrence of Functional Gastrointestinal Disorders in Children with Cow's Milk Allergy. J Pediatr. 2019;213:137. 10.1016/j.jpeds.2019.06.004
  10. Hojsak I. Probiotics in Functional Gastrointestinal Disorders. Adv Exp Med Biol. 2019;1125:121. 10.1007/5584_2018_321
  11. Han X, Lee A, Huang S, Gao J, Spence JR, et al. Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids. Gut Microbes. 2019;10:59. 10.1080/19490976.2018.1479625
  12. Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. 10.3920/BM2017.0105
  13. Wegh CAM, Benninga MA, Tabbers MM. Effectiveness of Probiotics in Children With Functional Abdominal Pain Disorders and Functional Constipation: A Systematic Review. J Clin Gastroenterol. 2018;52 Suppl 1, Proceedings from the 9th Probiotics, Prebiotics and New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health Meeting, held in Rome, Italy from September 10 to 12, 2017:S10. 10.1097/MCG.0000000000001054
  14. Darbaky Y, Evrard B, Patrier S, Falenta J, Garcin S, et al. Oral probiotic treatment of Lactobacillus rhamnosus Lcr35 prevents visceral hypersensitivity to a colonic inflammation and an acute psychological stress. J Appl Microbiol. 2017;122:188. 10.1111/jam.13320
  15. Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. 10.3164/jcbn.15-14
  16. Cruchet S, Furnes R, Maruy A, Hebel E, Palacios J, et al. The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts. Paediatr Drugs. 2015;17:199. 10.1007/s40272-015-0124-6
  17. Koc F, Arendt E, Coffey A, Ross RP, Stanton C. Impact of low FODMAP sourdough bread on gut microbiota using an colonic fermentation model. Front Microbiol. 2024;15:1496022. 10.3389/fmicb.2024.1496022
  18. Andreozzi V, Cuoco S, Balestrieri M, Fierro F, Ferrara N, et al. Synbiotic supplementation may globally improve non-motor symptoms in patients with stable Parkinson's disease: results from an open label single-arm study. Sci Rep. 2024;14:23095. 10.1038/s41598-024-74400-w
  19. Garvey SM, LeMoire A, Wang J, Lin L, Sharif B, et al. Safety and Tolerability of Microbial Inulinase Supplementation in Healthy Adults: A Randomized, Placebo-Controlled Trial. Gastro Hep Adv. 2024;3:920. 10.1016/j.gastha.2024.05.013
  20. Isakov VA, Pilipenko VI, Vlasova AV, Kochetkova AA. Evaluation of the Efficacy of Kombucha-Based Drink Enriched with Inulin and Vitamins for the Management of Constipation-Predominant Irritable Bowel Syndrome in Females: A Randomized Pilot Study. Curr Dev Nutr. 2023;7:102037. 10.1016/j.cdnut.2023.102037
  21. Pilipenko VI, Isakov VA, Morozov SV, Vlasova AV, Kochetkova AA. [Efficacy of newly developed kombucha-based specialized food product for treatment of constipation-predominant irritable bowel syndrome]. Vopr Pitan. 2022;91:95. 10.33029/0042-8833-2022-91-5-95-104
  22. Ochoa KC, Samant S, Liu A, Duysburgh C, Marzorati M, et al. In Vitro Efficacy of Targeted Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Enzymatic Digestion in a High-Fidelity Simulated Gastrointestinal Environment. Gastro Hep Adv. 2023;2:283. 10.1016/j.gastha.2022.10.011
  23. Bărboi OB, Chirilă I, Ciortescu I, Anton C, Drug VL. Inulin, Choline and Silymarin in the Treatment of Irritable Bowel Syndrome with Constipation-Randomized Case-Control Study. J Clin Med. 2022;11. 10.3390/jcm11082248
  24. Gunn D, Abbas Z, Harris HC, Major G, Hoad C, et al. Psyllium reduces inulin-induced colonic gas production in IBS: MRI and fermentation studies. Gut. 2022;71:919. 10.1136/gutjnl-2021-324784
  25. Bărboi OB, Ciortescu I, Chirilă I, Anton C, Drug V. Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review). Exp Ther Med. 2020;20:185. 10.3892/etm.2020.9315
  26. Ahluwalia B, Magnusson MK, Böhn L, Störsrud S, Larsson F, et al. Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2020;32:e13860. 10.1111/nmo.13860
  27. Abhari K, Saadati S, Hosseini-Oskouiee F, Yari Z, Hosseini H, et al. Is Bacillus coagulans supplementation plus low FODMAP diet superior to low FODMAP diet in irritable bowel syndrome management?. Eur J Nutr. 2020;59:2111. 10.1007/s00394-019-02060-y
  28. Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. 10.5152/tjg.2016.16301
  29. Major G, Pritchard S, Murray K, Alappadan JP, Hoad CL, et al. Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome. Gastroenterology. 2017;152:124. 10.1053/j.gastro.2016.09.062
  30. Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Using a multicomponent functional food in IBS patients with constipation a comparative controlled study]. Vopr Pitan. 2016;85:84.
  31. Bogovič Matijašić B, Obermajer T, Lipoglavšek L, Sernel T, Locatelli I, et al. Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial. J Dairy Sci. 2016;99:5008. 10.3168/jds.2015-10743
  32. Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study]. Vopr Pitan. 2015;84:83.
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